Largest one day declines
The 50 largest one day percentage moves lower recorded at the latest close. The largest moves were MRNA at −5.8% and JAZZ at −4.2%. By size, the list splits into 8 mega cap and 42 large cap listings.
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| Ticker | Company | Market cap (USD) | Size | 1D return | 1Y return |
|---|---|---|---|---|---|
| MRNA | Moderna, Inc. | $59.75B | Large cap | −5.77% | +496.25% |
| JAZZ | Jazz Pharmaceuticals plc | $16.89B | Large cap | −4.20% | +100.35% |
| LLY | Eli Lilly and Company | $1.06T | Mega cap | −3.59% | +62.80% |
| BSX | Boston Scientific Corporation | $69.81B | Large cap | −3.39% | −54.50% |
| CORT | Corcept Therapeutics Incorporated | $12.95B | Large cap | −3.05% | +71.81% |
| NVO | Novo Nordisk A/S | $208.63B | Mega cap | −3.02% | −13.32% |
| REGN | Regeneron Pharmaceuticals, Inc. | $83.89B | Large cap | −2.25% | +39.36% |
| MRK | Merck & Co., Inc. | $377.72B | Mega cap | −2.14% | +86.85% |
| HALO | Halozyme Therapeutics, Inc. | $12.41B | Large cap | −2.07% | +46.30% |
| AZN | AstraZeneca PLC | $263.12B | Mega cap | −2.00% | +5.09% |
| GMAB | Genmab A/S | $21.42B | Large cap | −1.78% | +36.20% |
| ABT | Abbott Laboratories | $198.74B | Large cap | −1.75% | −11.83% |
| PHG | Koninklijke Philips N.V. | $26.38B | Large cap | −1.60% | +1.27% |
| NVS | Novartis AG | $299.44B | Mega cap | −1.53% | +27.93% |
| BNTX | BioNTech SE | $28.28B | Large cap | −1.31% | +9.27% |
| SNY | Sanofi | $108.83B | Large cap | −1.30% | −4.33% |
| BBIO | BridgeBio Pharma, Inc. | $15.52B | Large cap | −1.28% | +60.05% |
| GSK | GSK plc | $104.29B | Large cap | −1.23% | +32.23% |
| INCY | Incyte Corporation | $25.97B | Large cap | −1.23% | +51.01% |
| ABVX | ABIVAX Société Anonyme | $10.17B | Large cap | −1.20% | +46.70% |
| JNJ | Johnson & Johnson | $658.24B | Mega cap | −1.15% | +55.40% |
| ABBV | AbbVie Inc. | $469.68B | Mega cap | −1.09% | +29.36% |
| EXEL | Exelixis, Inc. | $14.05B | Large cap | −1.09% | +45.68% |
| ASND | Ascendis Pharma A/S | $16.41B | Large cap | −1.08% | +29.66% |
| VRTX | Vertex Pharmaceuticals Incorporated | $138.63B | Large cap | −1.01% | +40.66% |
| RDY | Dr. Reddy's Laboratories Limited | $10.18B | Large cap | −0.97% | −14.19% |
| ALC | Alcon Inc. | $35.13B | Large cap | −0.95% | −10.24% |
| PFE | Pfizer Inc. | $161.30B | Large cap | −0.95% | +18.72% |
| MCK | McKesson Corporation | $104.54B | Large cap | −0.93% | +31.57% |
| KYMR | Kymera Therapeutics, Inc. | $10.53B | Large cap | −0.86% | +197.09% |
| CRL | Charles River Laboratories International, Inc. | $14.09B | Large cap | −0.85% | +81.27% |
| GEHC | GE HealthCare Technologies Inc. | $33.35B | Large cap | −0.81% | −1.15% |
| BMRN | BioMarin Pharmaceutical Inc. | $12.70B | Large cap | −0.77% | +11.85% |
| RGEN | Repligen Corporation | $10.25B | Large cap | −0.77% | +51.67% |
| VEEV | Veeva Systems Inc. | $39.78B | Large cap | −0.76% | −16.58% |
| TAK | Takeda Pharmaceutical Company Limited | $58.60B | Large cap | −0.65% | +22.68% |
| LH | Labcorp Holdings Inc. | $27.39B | Large cap | −0.58% | +21.14% |
| BMY | Bristol-Myers Squibb Company | $138.03B | Large cap | −0.52% | +47.01% |
| COO | The Cooper Companies, Inc. | $14.25B | Large cap | −0.49% | −1.93% |
| FMS | Fresenius Medical Care AG | $12.51B | Large cap | −0.47% | −3.21% |
| TEVA | Teva Pharmaceutical Industries Limited | $44.19B | Large cap | −0.47% | +110.08% |
| GILD | Gilead Sciences, Inc. | $184.47B | Large cap | −0.46% | +32.51% |
| ALNY | Alnylam Pharmaceuticals, Inc. | $32.12B | Large cap | −0.45% | −47.38% |
| GKOS | Glaukos Corporation | $10.65B | Large cap | −0.45% | +89.83% |
| BIO | Bio-Rad Laboratories, Inc. | $10.40B | Large cap | −0.44% | +32.71% |
| AMGN | Amgen Inc. | $238.06B | Mega cap | −0.43% | +56.24% |
| RPRX | Royalty Pharma plc | $35.71B | Large cap | −0.43% | +74.00% |
| PEN | Penumbra, Inc. | $12.72B | Large cap | −0.41% | +21.02% |
| ISRG | Intuitive Surgical, Inc. | $133.22B | Large cap | −0.38% | −21.38% |
| RMD | ResMed Inc. | $34.13B | Large cap | −0.38% | −15.77% |
Covers ~22,000 companies across the US, Europe and Asia-Pacific (ex mainland China, Hong Kong and India), refreshed nightly. Every listed stock opens as a full analysis for $9.90.
Micro and small cap listings are left out, so the list describes the market rather than thin trading, as are moves beyond 1,000% in a session, which are corporate actions the price series has not been restated for. This is a description of one day of price movement, nothing more. It says nothing about any company behind it.