Largest one day declines
The 50 largest one day percentage moves lower recorded at the latest close. The largest moves were SIG.AX at −8.8% and M1RN34.SA at −6.1%. By size, the list splits into 9 mega cap and 41 large cap listings.
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| Ticker | Company | Market cap (USD) | Size | 1D return | 1Y return |
|---|---|---|---|---|---|
| SIG.AX | Sigma Healthcare Limited | $21.65B | Large cap | −8.80% | −15.21% |
| M1RN34.SA | Moderna, Inc. | $63.51B | Large cap | −6.11% | +462.13% |
| MRNA | Moderna, Inc. | $59.75B | Large cap | −5.77% | +496.25% |
| JAZZ | Jazz Pharmaceuticals plc | $16.89B | Large cap | −4.20% | +100.35% |
| LLY | Eli Lilly and Company | $1.06T | Mega cap | −3.59% | +62.80% |
| BSX | Boston Scientific Corporation | $69.81B | Large cap | −3.39% | −54.50% |
| B1AX34.SA | Baxter International Inc. | $13.60B | Large cap | −3.38% | +3.61% |
| B1SX34.SA | Boston Scientific Corporation | $70.04B | Large cap | −3.08% | −89.24% |
| CORT | Corcept Therapeutics Incorporated | $12.95B | Large cap | −3.05% | +71.81% |
| NVO | Novo Nordisk A/S | $208.63B | Mega cap | −3.02% | −13.32% |
| REGN | Regeneron Pharmaceuticals, Inc. | $83.89B | Large cap | −2.25% | +39.36% |
| MRK | Merck & Co., Inc. | $377.72B | Mega cap | −2.14% | +86.85% |
| RDOR3.SA | Rede D'Or São Luiz S.A. | $14.92B | Large cap | −2.13% | +1.37% |
| HALO | Halozyme Therapeutics, Inc. | $12.41B | Large cap | −2.07% | +46.30% |
| DC4.DE | DexCom, Inc. | $33.35B | Large cap | −2.02% | +21.06% |
| AZN | AstraZeneca PLC | $263.12B | Mega cap | −2.00% | +5.09% |
| B1NT34.SA | BioNTech SE | $28.32B | Large cap | −1.96% | +2.68% |
| GMAB | Genmab A/S | $21.42B | Large cap | −1.78% | +36.20% |
| 7741.T | HOYA Corporation | $51.57B | Large cap | −1.76% | +28.99% |
| ABT | Abbott Laboratories | $198.74B | Large cap | −1.75% | −11.83% |
| SHL.DE | Siemens Healthineers AG | $51.23B | Large cap | −1.71% | −14.18% |
| FPH.AX | Fisher & Paykel Healthcare Corporation Limited | $15.44B | Large cap | −1.70% | +11.27% |
| 2M6.DE | Medtronic plc | $117.57B | Large cap | −1.63% | +2.65% |
| LILY34.SA | Eli Lilly and Company | $1.10T | Mega cap | −1.62% | +59.83% |
| PHG | Koninklijke Philips N.V. | $26.38B | Large cap | −1.60% | +1.27% |
| EL.PA | EssilorLuxottica Société anonyme | $85.31B | Large cap | −1.58% | −38.15% |
| NVS | Novartis AG | $299.44B | Mega cap | −1.53% | +27.93% |
| QS51.DE | Straumann Holding AG | $18.40B | Large cap | −1.51% | −1.10% |
| PME.AX | Pro Medicus Limited | $13.66B | Large cap | −1.48% | −39.15% |
| ESL.DE | EssilorLuxottica Société anonyme | $85.76B | Large cap | −1.45% | −39.11% |
| 4519.T | Chugai Pharmaceutical Co., Ltd. | $71.92B | Large cap | −1.39% | +9.21% |
| BNTX | BioNTech SE | $28.28B | Large cap | −1.31% | +9.27% |
| SNY | Sanofi | $108.83B | Large cap | −1.30% | −4.33% |
| 068270.KS | Celltrion, Inc. | $31.91B | Large cap | −1.29% | +11.19% |
| SN.L | Smith & Nephew plc | $12.18B | Large cap | −1.29% | −22.42% |
| BBIO | BridgeBio Pharma, Inc. | $15.52B | Large cap | −1.28% | +60.05% |
| GSK | GSK plc | $104.29B | Large cap | −1.23% | +32.23% |
| INCY | Incyte Corporation | $25.97B | Large cap | −1.23% | +51.01% |
| IUI1.DE | Intuitive Surgical, Inc. | $131.98B | Large cap | −1.22% | −21.06% |
| ABVX | ABIVAX Société Anonyme | $10.17B | Large cap | −1.20% | +46.70% |
| 4502.T | Takeda Pharmaceutical Company Limited | $58.08B | Large cap | −1.18% | +36.03% |
| 4503.T | Astellas Pharma Inc. | $26.88B | Large cap | −1.16% | +53.57% |
| JNJ | Johnson & Johnson | $658.24B | Mega cap | −1.15% | +55.40% |
| I1DX34.SA | IDEXX Laboratories, Inc. | $44.35B | Large cap | −1.11% | −17.31% |
| 4507.T | Shionogi & Co., Ltd. | $15.45B | Large cap | −1.09% | +15.63% |
| ABBV | AbbVie Inc. | $469.68B | Mega cap | −1.09% | +29.36% |
| EXEL | Exelixis, Inc. | $14.05B | Large cap | −1.09% | +45.68% |
| ASND | Ascendis Pharma A/S | $16.41B | Large cap | −1.08% | +29.66% |
| ABL.DE | Abbott Laboratories | $200.44B | Mega cap | −1.06% | −10.02% |
| VRTX | Vertex Pharmaceuticals Incorporated | $138.63B | Large cap | −1.01% | +40.66% |
Covers ~22,000 companies across the US, Europe and Asia-Pacific (ex mainland China, Hong Kong and India), refreshed nightly. Every listed stock opens as a full analysis for $9.90.
Micro and small cap listings are left out, so the list describes the market rather than thin trading, as are moves beyond 1,000% in a session, which are corporate actions the price series has not been restated for. This is a description of one day of price movement, nothing more. It says nothing about any company behind it.