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Largest one day declines

The 50 largest one day percentage moves lower recorded at the latest close. The largest moves were M1RN34.SA at −6.1% and MRNA at −5.8%. By size, the list splits into 11 mega cap and 39 large cap listings.

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50 of 23,178 companies match these filters.Clear filters

TickerCompanyMarket cap (USD)Size1D return1Y return
M1RN34.SAModerna, Inc.$63.51BLarge cap−6.11%+462.13%
MRNAModerna, Inc.$59.75BLarge cap−5.77%+496.25%
JAZZJazz Pharmaceuticals plc$16.89BLarge cap−4.20%+100.35%
LLYEli Lilly and Company$1.06TMega cap−3.59%+62.80%
BSXBoston Scientific Corporation$69.81BLarge cap−3.39%−54.50%
B1AX34.SABaxter International Inc.$13.60BLarge cap−3.38%+3.61%
B1SX34.SABoston Scientific Corporation$70.04BLarge cap−3.08%−89.24%
CORTCorcept Therapeutics Incorporated$12.95BLarge cap−3.05%+71.81%
NVONovo Nordisk A/S$208.63BMega cap−3.02%−13.32%
REGNRegeneron Pharmaceuticals, Inc.$83.89BLarge cap−2.25%+39.36%
MRKMerck & Co., Inc.$377.72BMega cap−2.14%+86.85%
RDOR3.SARede D'Or São Luiz S.A.$14.92BLarge cap−2.13%+1.37%
HALOHalozyme Therapeutics, Inc.$12.41BLarge cap−2.07%+46.30%
AZNAstraZeneca PLC$263.12BMega cap−2.00%+5.09%
B1NT34.SABioNTech SE$28.32BLarge cap−1.96%+2.68%
GMABGenmab A/S$21.42BLarge cap−1.78%+36.20%
ABTAbbott Laboratories$198.74BLarge cap−1.75%−11.83%
LILY34.SAEli Lilly and Company$1.10TMega cap−1.62%+59.83%
PHGKoninklijke Philips N.V.$26.38BLarge cap−1.60%+1.27%
NVSNovartis AG$299.44BMega cap−1.53%+27.93%
BNTXBioNTech SE$28.28BLarge cap−1.31%+9.27%
SNYSanofi$108.83BLarge cap−1.30%−4.33%
BBIOBridgeBio Pharma, Inc.$15.52BLarge cap−1.28%+60.05%
GSKGSK plc$104.29BLarge cap−1.23%+32.23%
INCYIncyte Corporation$25.97BLarge cap−1.23%+51.01%
ABVXABIVAX Société Anonyme$10.17BLarge cap−1.20%+46.70%
JNJJohnson & Johnson$658.24BMega cap−1.15%+55.40%
I1DX34.SAIDEXX Laboratories, Inc.$44.35BLarge cap−1.11%−17.31%
ABBVAbbVie Inc.$469.68BMega cap−1.09%+29.36%
EXELExelixis, Inc.$14.05BLarge cap−1.09%+45.68%
ASNDAscendis Pharma A/S$16.41BLarge cap−1.08%+29.66%
VRTXVertex Pharmaceuticals Incorporated$138.63BLarge cap−1.01%+40.66%
JNJB34.SAJohnson & Johnson$658.09BMega cap−0.98%+47.82%
RDYDr. Reddy's Laboratories Limited$10.18BLarge cap−0.97%−14.19%
ALCAlcon Inc.$35.13BLarge cap−0.95%−10.24%
PFEPfizer Inc.$161.30BLarge cap−0.95%+18.72%
MCKMcKesson Corporation$104.54BLarge cap−0.93%+31.57%
ABTT34.SAAbbott Laboratories$199.23BLarge cap−0.90%−16.35%
A1ZN34.SAAstraZeneca PLC$258.63BMega cap−0.86%+0.13%
KYMRKymera Therapeutics, Inc.$10.53BLarge cap−0.86%+197.09%
CRLCharles River Laboratories International, Inc.$14.09BLarge cap−0.85%+81.27%
GEHCGE HealthCare Technologies Inc.$33.35BLarge cap−0.81%−1.15%
BMRNBioMarin Pharmaceutical Inc.$12.70BLarge cap−0.77%+11.85%
RGENRepligen Corporation$10.25BLarge cap−0.77%+51.67%
VEEVVeeva Systems Inc.$39.78BLarge cap−0.76%−16.58%
N1VO34.SANovo Nordisk A/S$208.90BMega cap−0.75%−17.86%
TAKTakeda Pharmaceutical Company Limited$58.60BLarge cap−0.65%+22.68%
REGN34.SARegeneron Pharmaceuticals, Inc.$85.16BLarge cap−0.59%+33.80%
LHLabcorp Holdings Inc.$27.39BLarge cap−0.58%+21.14%
BMYBristol-Myers Squibb Company$138.03BLarge cap−0.52%+47.01%

Covers ~22,000 companies across the US, Europe and Asia-Pacific (ex mainland China, Hong Kong and India), refreshed nightly. Every listed stock opens as a full analysis for $9.90.

Micro and small cap listings are left out, so the list describes the market rather than thin trading, as are moves beyond 1,000% in a session, which are corporate actions the price series has not been restated for. This is a description of one day of price movement, nothing more. It says nothing about any company behind it.

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